Molecular Formula | C20H23NO3 |
Molar Mass | 325.4 |
Appearance | neat |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Hazard Symbols | N - Dangerous for the environment |
Risk Codes | 51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | 61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN3077 9/PG 3 |
WGK Germany | 2 |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Overview | on 21 November 2013, the European Commission for the issuance of implementing Regulation (EU) No 2013/1, (EU)NO1176/2013(EU), NO1177/2013, amendment of annex to Regulation (EU)NO540/2011, approval of the active substances benzalenin, pyridamole, spironolactone ethyl ester is put on the market as a plant protection product, and is valid from May 1, 2014 to April 30, 2024. The regulations will come into force on the 20th day of promulgation and will be formally implemented on May 1, 2014. Jingbenfulin (benalaxyl-M) was reported by Saig in Italy in, mainly used for the prevention and control of diseases caused by oomycetes fungi, such as downy mildew, late blight and rot fungi. Jingbenfuling, IUPAC chemical name N-phenyl acetyl-N-2, 6-xylyl-d-alanine methyl ester, CAS No. 98243-83-5, empirical formula C20H23NO3, relative molecular mass 325.4. |
Toxicology | acute oral toxicity of jingbenfuling in rats LD50> 2000mg/kg.; acute percutaneous toxicity LD50> 2000mg/kg; Rat acute inhalation toxicity LC50>4.42mg/L, no irritation to the skin and eyes of rats, no sensitization to the skin of guinea pigs. No teratogenicity, carcinogenicity and mutagenicity. It is rapidly metabolized in mammals, rapidly excreted in urine and feces two days after administration, and metabolized to glycosides in plants. Soil Microbial degradation is a major metabolic pathway in the environment. The metabolism in soil is slow, and the degradation half-life DT50 in aerobic soil is 36~124 days (4 kinds of typical soil) under the experimental condition of 20. At the same time, refined benzene Frost spirit has low toxicity to birds, algae, Daphnia, bees, earthworms and other environmental organisms. |
pharmacological action | it mainly interferes with the biosynthesis of rRNA by affecting the activity of endogenous RNA polymerase. In addition, studies have shown that the membrane function of pathogenic bacteria is also secondary. Therefore, it can inhibit the germination of zoospores of pathogenic bacteria and induce the leakage of amino acids in mycelium. The medicine can be rapidly absorbed by plant roots, stems and leaves, and transmitted to various parts in the plant body, including the growing point. The protective effect is mainly through inhibiting the germination of pathogen spores and the growth of mycelium, and the therapeutic effect is mainly to inhibit the growth of mycelium, eradication is mainly through inhibition of spore formation. Spermedrol is highly selective and highly active against fungi belonging to the phylum oomycetes, in particular, the fungi of Peronosporaceae, such as phytophhoraspp. Plasmoparaspp. Pseudoperonosupp. (Arthrobacter sp.) (Bremiaspp.) pythiumsp. Et al. Can be used for the production of potato, tomato and other solanaceous crops late blight, hops, grapes, lettuce, onions, soybeans, tobacco and other downy mildew. And Phytophthora caused by fungi strawberry blight, ornamental plant blight and rot caused by the genus turfgrass root rot. In addition to being used as a foliar treatment agent, melaxine can also be developed as a seed dressing agent in combination with other fungicides.